{"id":50810,"date":"2023-04-20T05:20:25","date_gmt":"2023-04-20T05:20:25","guid":{"rendered":"http:\/\/southafricavoice.com\/?guid=908cfa6828801e60ac04913e407ba65b"},"modified":"2023-04-20T05:20:25","modified_gmt":"2023-04-20T05:20:25","slug":"les-geneticiens-de-la-reproduction-reunis-a-paris-presentent-le-tout-premier-test-de-sequencage-du-genome-entier-dans-des-embryons","status":"publish","type":"post","link":"https:\/\/southafricavoice.com\/les-geneticiens-de-la-reproduction-reunis-a-paris-presentent-le-tout-premier-test-de-sequencage-du-genome-entier-dans-des-embryons\/","title":{"rendered":"Les g\u00e9n\u00e9ticiens de la reproduction r\u00e9unis \u00e0 Paris pr\u00e9sentent le tout premier test de s\u00e9quen\u00e7age du g\u00e9nome entier dans des embryons"},"content":{"rendered":"<div>\n<ul>\n<li><strong>Le Dr\u00a0Santiago Munn\u00e9, un pionnier du diagnostic g\u00e9n\u00e9tique pr\u00e9implantatoire, a pr\u00e9sent\u00e9 le nouveau test lors de la Conf\u00e9rence PGDIS<\/strong><\/li>\n<li><strong>Non seulement ce nouveau test de laboratoire d\u00e9tectera les g\u00e8nes h\u00e9rit\u00e9s des parents, mais il r\u00e9v\u00e8lera \u00e9galement les nouvelles mutations pouvant mener \u00e0 des maladies \u00ab\u00a0de novo\u00a0\u00bb comme l&#8217;autisme<\/strong><\/li>\n<\/ul>\n<p style=\"text-align: left;\" align=\"justify\">PARIS, 20 avr. 2023 (GLOBE NEWSWIRE) &#8212; Le Dr\u00a0Santiago Munn\u00e9, pionnier du diagnostic g\u00e9n\u00e9tique pr\u00e9implantatoire, a pr\u00e9sent\u00e9 le premier test de s\u00e9quen\u00e7age du g\u00e9nome entier sur des embryons devant les participants \u00e0 la 20e\u00a0Conf\u00e9rence de la Soci\u00e9t\u00e9 internationale de diagnostic g\u00e9n\u00e9tique pr\u00e9implantatoire (PGDIS pour Preimplantation Genetic Diagnosis International Society), organis\u00e9e cette semaine \u00e0 Paris.<\/p>\n<p style=\"text-align: left;\" align=\"justify\">Lors de son allocution pl\u00e9ni\u00e8re \u00e0 laquelle ont assist\u00e9 plus de 300\u00a0experts, le Dr\u00a0Munn\u00e9, un pr\u00e9curseur de la g\u00e9n\u00e9tique de la reproduction de renomm\u00e9e internationale, a pr\u00e9sent\u00e9 des donn\u00e9es de validation pour GenomeScreen<img decoding=\"async\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/14.0.0\/72x72\/2122.png\" alt=\"\u2122\" class=\"wp-smiley\" style=\"height: 1em; max-height: 1em;\" \/>, le test d\u00e9velopp\u00e9 par l&#8217;\u00e9quipe de recherche qu&#8217;il dirige dans la soci\u00e9t\u00e9 de biotechnologie GenEmbryomics.<\/p>\n<p style=\"text-align: left;\" align=\"justify\">\u00ab\u00a0Nous savions, depuis que nous avons commenc\u00e9 \u00e0 travailler sur le diagnostic embryonnaire en\u00a01993, que la s\u00e9lection embryonnaire serait d\u00e9terminante pour la grossesse, surtout chez les patientes plus \u00e2g\u00e9es. Au cours des 30\u00a0derni\u00e8res ann\u00e9es, notre travail s&#8217;est concentr\u00e9 sur l&#8217;am\u00e9lioration de la s\u00e9lection embryonnaire g\u00e9n\u00e9tique, m\u00eame si l&#8217;approche diagnostique d\u00e9finitive (celle qui fournit le plus d&#8217;informations et les meilleurs r\u00e9sultats) sera sans aucun doute celle-ci\u00a0: le s\u00e9quen\u00e7age du g\u00e9nome entier de l&#8217;embryon \u00e0 l&#8217;aide de quelques cellules seulement obtenues \u00e0 partir d&#8217;une biopsie. Ce test va ouvrir des portes dont nous ignorions jusqu&#8217;\u00e0 l&#8217;existence\u00a0\u00bb, a d\u00e9clar\u00e9 le Dr\u00a0Munn\u00e9 sur le travail accompli chez GenEmbryomics.<\/p>\n<p style=\"text-align: left;\" align=\"justify\"><strong>Comprendre le g\u00e9nome, cela signifie tout savoir sur un embryon avant le transfert<\/strong><br \/>\nGenomeScreen<img decoding=\"async\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/14.0.0\/72x72\/2122.png\" alt=\"\u2122\" class=\"wp-smiley\" style=\"height: 1em; max-height: 1em;\" \/> est un nouveau test r\u00e9volutionnaire sur le s\u00e9quen\u00e7age du g\u00e9nome entier pour les embryons issus de FIV, qui a \u00e9t\u00e9 d\u00e9crit par les autorit\u00e9s comme \u00ab\u00a0le test g\u00e9n\u00e9tique le plus complet dans la FIV\u00a0\u00bb lors du forum\u00a0<strong><em>PGDIS<\/em><\/strong>.<\/p>\n<p style=\"text-align: left;\" align=\"justify\">Le test apporte des renseignements extr\u00eamement pr\u00e9cis sur la s\u00e9quence du g\u00e9nome de l&#8217;embryon et sur les parents g\u00e9n\u00e9tiques, fournissant aux familles des informations pr\u00e9implantatoires d\u00e9terminantes sur la sant\u00e9 de l&#8217;embryon et le pronostic de reproduction pouvant \u00e9clairer leurs d\u00e9cisions. Par ailleurs, ces informations seront inestimables pour les personnes n\u00e9es d&#8217;une FIV, car elles fourniront des donn\u00e9es sur la nutrig\u00e9nomique ou des conseils sur les m\u00e9dicaments les plus g\u00e9n\u00e9tiquement adapt\u00e9s au\/\u00e0 la patient(e).<\/p>\n<p style=\"text-align: left;\" align=\"justify\">\u00ab\u00a0Au tout d\u00e9but de nos recherches sur le s\u00e9quen\u00e7age d&#8217;embryons, notre objectif \u00e9tait de cr\u00e9er un outil complet et puissant, qui pourrait doter les m\u00e9decins de la fertilit\u00e9 de donn\u00e9es exhaustives pour des d\u00e9pistages de pr\u00e9cision\u00a0\u00bb, s&#8217;est souvenu le Dr\u00a0Nick Murphy, fondateur de GenEmbryomics. \u00ab\u00a0Maintenant que nous avons cet outil et que nous l&#8217;utilisons avec une fiabilit\u00e9 de 99\u00a0%, nous avons conscience que ce diagnostic nous fournit des informations, mais am\u00e9liore \u00e9galement consid\u00e9rablement le succ\u00e8s de la m\u00e9decine de reproduction\u00a0\u00bb, a ajout\u00e9 le Dr\u00a0Murphy.<\/p>\n<p style=\"text-align: left;\" align=\"justify\"><strong>Le s\u00e9quen\u00e7age des embryons va augmenter les taux de r\u00e9ussite des FIV<\/strong><\/p>\n<p style=\"text-align: left;\" align=\"justify\">Le professeur\u00a0Munn\u00e9, dont la carri\u00e8re en tant que chef de file en g\u00e9n\u00e9tique reproductive s&#8217;\u00e9tend sur plus de 20\u00a0ans, a apport\u00e9 d&#8217;\u00e9normes contributions \u00e0 la s\u00e9lection embryonnaire et au traitement de FIV. Avec ce test, lui et son \u00e9quipe de chercheurs solidifient le r\u00f4le des tests g\u00e9n\u00e9tiques dans la m\u00e9decine de reproduction, augmentant le succ\u00e8s des traitements.<\/p>\n<p style=\"text-align: left;\" align=\"justify\">Selon le professeur\u00a0Munn\u00e9\u00a0: \u00ab\u00a0Les conclusions pr\u00e9sent\u00e9es lors de la conf\u00e9rence constituent les donn\u00e9es de validation d&#8217;un test qui va changer la s\u00e9lection embryonnaire telle que nous la connaissons\u00a0\u00bb. \u00ab\u00a0L&#8217;analyse g\u00e9n\u00e9tique pr\u00e9implantatoire avec s\u00e9quen\u00e7age du g\u00e9nome entier repr\u00e9sente un pas de g\u00e9ant\u00a0: entre autres choses, elle nous dira quels embryons s&#8217;implanteront avec succ\u00e8s, car nous saurons \u00e0 l&#8217;avance lesquels sont vraiment en bonne sant\u00e9, c&#8217;est-\u00e0-dire sans maladie h\u00e9rit\u00e9e des parents ou sans maladie de novo, comme l&#8217;autisme\u00a0\u00bb, a-t-il conclu.<\/p>\n<p style=\"text-align: left;\" align=\"justify\"><strong>\u00c0 propos de GenEmbryomics<\/strong><br \/>\nFond\u00e9e par le Dr Nick Murphy en 2019, GenEmbryomics est une soci\u00e9t\u00e9 de biotechnologie de pointe sp\u00e9cialis\u00e9e dans l&#8217;analyse g\u00e9nomique des embryons afin de d\u00e9terminer les candidats les plus viables pour une implantation par FIV. Son travail conduira \u00e0 des taux de r\u00e9ussite plus \u00e9lev\u00e9s dans les cycles de FIV, gr\u00e2ce \u00e0 ses algorithmes propri\u00e9taires qui permettent une s\u00e9lection embryonnaire plus pr\u00e9cise et plus efficace, bas\u00e9e sur le g\u00e9nome entier de chaque embryon.<img decoding=\"async\" src=\"https:\/\/ci3.googleusercontent.com\/proxy\/ZxIk2u2nsbFZkNWFBylpmrzWmQbSnfRV6KlwjaKzfFJI3Fp64SLDUda-x3Pzz1fNCrXuaQbZiN4tJficEe_3eZSw9BRNHqOz_9-Ou1NU7_w2TkTDb1b8vhKwWeiKAmfJGLMGDwNtlWTFU9D5zoRhyDD8Fr-wY9kmqHDlLTXTy41E7KCThIdOUDs=s0-d-e1-ft#https:\/\/ml.globenewswire.com\/media\/NGRiNzE4YjUtOWQwMS00NGJmLWEzNmMtMTVjYTI3MDk2MjU0LTEyNjkzMDY=\/tiny\/GenEmbryomics.png\" \/><\/p>\n<pre>Pour tout compl\u00e9ment d'information\r\nDulce Iborra Candela\r\n+34 647942875\r\n<a href=\"mailto:dulce@laembajadora.es\"  rel=\"noopener noreferrer\">dulce@laembajadora.es<\/a><\/pre>\n<p align=\"center\">GlobeNewswire Distribution ID 8811736<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Le Dr\u00a0Santiago Munn\u00e9, un pionnier du diagnostic g\u00e9n\u00e9tique pr\u00e9implantatoire, a pr\u00e9sent\u00e9 le nouveau test lors de la Conf\u00e9rence PGDIS Non seulement ce nouveau test de laboratoire d\u00e9tectera les g\u00e8nes h\u00e9rit\u00e9s des parents, mais il r\u00e9v\u00e8lera \u00e9galement les nouvelles mutations pouvant mener \u00e0 des maladies \u00ab\u00a0de novo\u00a0\u00bb comme l\u2019autisme PARIS, 20 avr. 2023 (GLOBE NEWSWIRE) \u2014 [\u2026]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[261],"tags":[165,166],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - 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